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EPAR Technical Report #345
Review of Literature on Factors Affecting Private Sector Investment in Global Health R&D
Publication Date: 12/01/2017
Type: Literature Review
Abstract

The share of private sector funding, relative to public sector funding, for drug, vaccine, and diagnostic research & development (R&D) differs considerably across diseases. Private sector investment in overall health R&D exceeds $150 billion annually, but is largely concentrated on non-communicable chronic diseases with only an estimated $5.9 billion focused on "global health", targeting diseases that primarily affect low and middle-income countries (LMICs). We examine the evidence for five specific disincentives to private sector global health R&D investment: scientific uncertainty, weak policy environments, limited revenues and market uncertainty, high fixed and sunk costs, and downstream rents from imperfect markets. Though all five may affect estimates of net returns from an investment decision, they are worth examining separately as each calls for a different intervention or remediation to change behavior.

Technical Report, Technical Report Executive Summary
EPAR Technical Report #349
Aid and Economic Self-Sufficiency
Publication Date: 11/30/2017
Type: Literature Review
Abstract

Donor countries and multilateral organizations may pursue multiple goals with foreign aid, including supporting low-income country development for strategic/security purposes (national security, regional political stability) and for short-and long-term economic interests (market development and access, local and regional market stability). While the literature on the effectiveness of aid in supporting progress on different indicators of country development is inconclusive, donors are interested in evidence that aid funding is not permanent but rather contributes to a process by which recipient countries develop to a point that they are economically self-sufficient. In this report, we review the literature on measures of country self-sufficiency and descriptive evidence from illustrative case studies to explore conditions associated with transitions toward self-sufficiency in certain contexts.

  

Technical Report, Case Study - Botswana, Case Study - Indonesia, Case Study - India, Case Study - Ghana, Case Study - Rwanda
EPAR Technical Report #200
Herbicide Resistant Cassava
Publication Date: 08/24/2012
Type: Literature Review
Abstract

This report investigates the potential environmental and socio-economic benefits and costs of glyphosate resistant cassava.  Glyphosate resistant crops (also referred to as glyphosate tolerant) have been rapidly adopted by a number of crop producers because they simplify and/or reduce the cost of weed management. Glyphosate resistant crops also provide external environmental benefits by promoting reduced tillage agriculture, decreasing erosion and increasing soil health. However, glyphosate resistant crops also have some environmental costs, potentially leading to increased use of herbicides and environmental contamination. Because transgenic glyphosate resistant cassava is not currently in use, literature on its potential environmental and socioeconomic costs and benefits is limited. Therefore, this report draws on the literature for glyphosate resistant crops that are in current use, including maize, soybeans, sugar beets and canola (rapeseed). We find that socioeconomic and environmental impacts of glyphosate resistant crops differ by crop-type, agroecological conditions, production systems and local regulatory structure. Therefore, some benefits and costs associated with other glyphosate resistant crops may not be applicable to glyphosate resistant cassava. 

Literature Review