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EPAR Technical Report #346
Publication Date: 04/23/2018
Type: Literature Review
Abstract

The private sector is the primary investor in health research and development (R&D) worldwide, with investment annual investment exceeding $150 billion, although only an estimated $5.9 billion is focused on diseases that primarily affect low and middle-income countries (LMICs) (West et al., 2017b). Pharmaceutical companies are the largest source of private spending on global health R&D focused on LMICs, providing $5.6 billion of the $5.9 billion in total private global health R&D per year. This report draws on 10-K forms filed by Pharmaceutical companies with the U.S. Securities and Exchange Commission (SEC) in the year 2016 to examine the evidence for five specific disincentives to private sector investment in drugs, vaccines and therapeutics for global health R&D: scientific uncertainty, weak policy environments, limited revenues and market uncertainty, high fixed costs for research and manufacturing, and imperfect markets. 10-K reports follow a standard format, including a business section and a risk section which include information on financial performance, investment options, lines of research, promising acquisitions and risk factors (scientific, market, and regulatory). As a result, these filings provide a valuable source of information for analyzing how private companies discuss risks and challenges as well as opportunities associated with global health R&D targeting LMICs.

EPAR Technical Report #287
Publication Date: 10/09/2014
Type: Literature Review
Abstract

This report draws on past and present peer-reviewed articles and published reports by institutions including the World Health Organization (WHO), the UK Department for International Development (DFID), and others to provide a scoping summary of the household-level spillovers and broader impacts of a select group of health initiatives. Rather than focusing on estimates of the direct health impacts of investments (e.g., reductions in mortality from vaccine delivery), we focus on estimates of the less-often reported spillover effects of specific health investments on household welfare or the broader economy. The brief is designed to give a concise overview of major theories linking health improvements to broader social and economic outcomes, followed by more in-depth summaries of available local- and country-level estimates of broader impacts, defined as project spillovers offering local, regional and national social and economic benefits not typically reported in project evaluations.

EPAR Technical Report #288
Publication Date: 09/17/2014
Type: Literature Review
Abstract

This report summarizes current trends in the application of Development Finance Institution (DFI)-based returnable capital finance in developing countries, with an emphasis on “pro-poor” development initiatives. We begin by reviewing the financial instruments used by DFIs. We then review the major DFI providers of returnable-capital based finance, drawing on past and present peer-reviewed articles and published reports exploring trends in the uses of different returnable capital instruments over time. Finally, we conclude by further examining recent efforts to use returnable capital to finance development initiatives explicitly targeting the poor.

EPAR Research Brief #285
Publication Date: 06/19/2014
Type: Literature Review
Abstract

This brief draws on recent reports by the OECD, the World Bank, the Overseas Development Institute (ODI), the Climate Policy Initiative (CPI) and others to provide an overview of climate finance in developing countries. The brief is divided into three sections: (i) sources of global climate finance; (ii) country-level flows of climate finance; and (iii) applications of climate finance in developing countries. The brief is designed to give a concise overview of financial flows directed at climate change mitigation and adaptation globally and in developing countries, with an introduction to climate finance accounting such that climate financial flow volumes can be compared to aid volumes in other sectors. Total global climate finance flows were approximately USD $364 billion in 2011 (Buchner et al., 2012) and $359 billion in 2012. However the vast majority of these flows - 76%, or $275 billion - was finance generated and spent within a country’s own borders (domestic finance) (Buchner et al., 2013). The “Fast-Start Finance” period from 2010-2012 saw $35 billion in new aid mobilized for climate finance in developing countries. Developed countries have recently committed to mobilize an additional $100 billion per year by 2020.

EPAR Research Brief #228
Publication Date: 04/18/2014
Type: Literature Review
Abstract

Cassava (Manihot esculenta Crantz) is a widely-grown staple food in the tropical and subtropical regions of Africa, Asia, and Latin America. In this brief we examine the environmental constraints to, and impacts of, smallholder cassava production systems in Sub-Saharan Africa (SSA) and South Asia (SA), noting where the analysis applies to only one of these regions. We highlight crop-environment interactions at three stages of the cassava value chain: pre-production (e.g., land clearing), production (e.g., soil, water, and input use), and post-production (e.g., crop storage). At each stage we emphasize environmental constraints on production (poor soil quality, water scarcity, crop pests, etc.) and also environmental impacts of crop production (e.g., soil erosion, water depletion and pesticide contamination). We then highlight good practices for overcoming environmental constraints and minimizing environmental impacts in smallholder cassava production systems. Evidence on environmental issues in smallholder cassava production is relatively thin, and unevenly distributed across regions. The literature on cassava in South Asian smallholder systems is limited, reflecting a crop of secondary importance (though it is widely found elsewhere in Asia such as South East Asia), in comparison to cassava in much of SSA. The majority of the research summarized in this brief is from SSA. The last row of Table 1 summarizes good practices currently identified in the literature. However, the appropriate strategy in a given situation will vary widely based on contextual factors, such as local environmental conditions, market access, cultural preferences, production practices and the policy environment.

EPAR Technical Report #254
Publication Date: 03/20/2014
Type: Literature Review
Abstract

This overview introduces a series of EPAR briefs in the Agriculture-Environment Series that examine crop-environment interactions for a range of crops in smallholder food production systems in Sub-Saharan Africa (SSA) and South Asia (SA). The briefs cover the following important food crops in those regions; rice (#208), maize (#218), sorghum/millets (#213), sweet potato/yam (#225), and cassava (#228).

Drawing on the academic literature and the field expertise of crop scientists, these briefs highlight crop-environment interactions at three stages of the crop value chain: pre-production (e.g., land clearing and tilling), production (such as water, nutrient and other input use), and post-production (e.g., waste disposal and crop storage). At each stage we emphasize environmental constraints on crop yields (including poor soils, water scarcity, crop pests) and impacts of crop production on the environment (such as soil erosion, water depletion and pest resistance). We then highlight best practices from the literature and from expert experience for minimizing negative environmental impacts in smallholder crop production systems.

This overview (along with the accompanying detailed crop briefs) seeks to provide a framework for stimulating across-crop discussions and informed debates on the full range of crop-environment interactions in agricultural development initiatives.

A paper based on this research series was published in Food Security in August 2015.

EPAR Technical Report #35
Publication Date: 05/13/2009
Type: Literature Review
Abstract

This report provides a general overview of trends in public and private agricultural research and development (R&D) funding and expenditures in Sub-Saharan Africa (SSA). The request is divided into two sections, covering public funding and private funding. Within each section, relevant data is presented on historical funding patterns, the types of research conducted, and which countries within SSA are financing R&D at the highest level. We find that the majority of growth in African public agricultural research funding took place in the 1960s, when real public spending on agricultural research increased 6% a year. From 1971 to 2000 annual growth averaged 1.4% a year. Public financing of agricultural R&D experienced a moderate shift in the 1990s from bilateral and multilateral donor funding to domestic government financing. The shift varied by country, but donor funding dropped for all SSA countries an average of 10%. Private research and development funding is heavily concentrated in developed countries with the United States and Japan the two biggest spenders. Within SSA, private R&D expenditures comprise 2% of all R&D spending. The main private actors in SSA are companies based in South Africa and Nigeria. The private sector is focused on research areas that involve marketable inputs, such as chemicals, seeds, and machines/

EPAR Technical Report #19
Publication Date: 02/06/2009
Type: Literature Review
Abstract

Special Economic Zones (SEZs) are generally defined as geographically delimited areas administered by a single body, offering certain incentives (duty-free importing and streamlined customs procedures, for instance) to businesses that physically locate within the zone. This literature review provides a baseline analysis of SEZs and their potential impacts on smallholder farmers in SSA. Criticism on SEZs is distinctly divided between those who criticize on social or environmental grounds versus those who question the economic impact of SEZs. SEZs are often criticized based on perceived negative socio-economic impacts—particularly their negative impact on women, labor, and working conditions. This review includes several country-specific studies that find evidence that SEZs actually have higher environmental standards and higher worker satisfaction than outside the SEZ. Most responses to criticisms do note, however, that the case studies’ results are not necessarily generalizable to SEZs throughout the world. The literature review includes key elements of successes and failures pulled from the case studies of SEZs in SSA. Though the evidence is insufficient to conclusively determine if smallholder farmers receive direct benefits from SEZs and their associated agroindustrial contracts, this review finds that resources provided to farmers (credit at rates lower than bank rates, technical or managerial assistance, pesticides, seeds, and fertilizer on credit) tend to be concentrated among larger farmers. The report concludes with a note on donor involvement as well as recommendations for further research.